Dra. Sara Terryn 

Current Position

2000 - 2006

PhD student and teaching assistent at the Faculty of Medicine 
Hasselt University /transnationale Universiteit Limburg, Campus Diepenbeek
Agoralaan - Building D
B-3590 Diepenbeek
Belgium  

Titel PhD project: Properties of the mouse proximal tubule in primary cell culture under control conditions and after acute or chronic exposure to heavy metals.

University Education

1996 - 2000: Master in Biomedical Sciences at the Free University of Brussels (VUB), Brussels, Belgium


Teaching

1st year medical students: fysical models in medical sciences (practical tests)

2nd year medical students: gastro-intestinal physiology

3d year medical students: cardiovascular physiology, pulmonary physiology and renal physiology


Membership Scientific Associations

American Society of Cell Biology (ASCB)

European Kidney Research Association (EKRA)

Belgian Society of Cell and Developmental Biology (BSCDB)

Belgisch Genootschap voor Fundamentele en Klinische Fysiologie en Pharmacologie (Belgian society for fundamental and clinical physiology and pharmacology)

Publication of articles in peer review journals

Darville MI, Terryn S, Eizirik DL. An octamer motif is required for activation of the inducible nitric oxide synthase promoter in pancreatic beta-cells. Endocrinology. 2004 Mar;145(3):1130-6. 

Publication of abstracts in peer review journals

• Abstracts for the “Autumn Meeting of the Belgian Society for fundamental and clinical physiology and pharmacology” of 16 november 2002 te Gent published in the European Journal of Physiology – Pflügers Archiv, 2003 nr. 445: R1-R8. Abstracts titled:
  1. A simple method to obtain a primary culture of highly differentiated mouse proximal tubular cells grown on collagen-coated membranes. Sara Terryn, Frank Vandenabeele, Paul Steels and Emmy Van Kerkhove.
  2. Transforming growth factor beta 1 (TGF-ß1) induces myofibroblast transdifferentiation in primary cultures of mouse proximal tubulus epithelial cells. Frank Vandenabeele, Sara Terryn, Marjan Moreels, Paul Steels, Emmy Van Kerkhove and Ivo Lambrichts.

• Abstract for “the world congress of nephrology” held from 8 to 12 june 2003 in Berlin; published in Nephology, Dialysis and Transplantation, volume 18, supplement 4, June 2003: Wednesday, June 11: Basic Science A16 Miscellaneaous W201. Abstract titled: Proximal tubule cells in primary culture, a model to study chronic Cadmium exposure and interstitial fibrosis. Transdifferentiation to myofibroblasts occurs in the presence of TGF-ß1. Sara Terryn, Frank Vandenabeele, Marjan Moreels, Paul Steels and Emmy Van Kerkhove.

• Abstract for “the American Society of Cell Biology” 43rd annual meeting from 13 to 17 december 2003 at San Francisco; published in Supplement to Molecular Biology of the cell, volume 14, November 2003: pg. 262a. Abstract titled: A primary culture of mouse proximal tubular cells cultured on collagen-coated membranes: characterization and usefulness in the study of nephrotoxic effects of Cadmium. Sara Terryn, Inge Smolders, Frank Vandenabeele, Paul Steels and Emmy Van Kerkhove.

Meetings and presentations

25.06.2001: Oral communication at the Lunchseminar at BIOMED: Sodium-glucose cotransport in alveolar cells.

25.06.2002 CMK-seminar: Kidney proximal tubule cells in primary culture: a model for the study of toxic substances.

01.07.2002 BIOMED lunchseminar: Kidney proximal tubule cells in primary culture: a model for the study of toxic substances.

16.11.2002: Posterpresentation at the Autumn Meeting of the Belgian Society for fundamental and clinical physiology and pharmacology in Gent titled: 1. A simple method to obtain a primary culture of highly differentiated mouse proximal tubular cells grown on collagen-coated membranes. Sara Terryn, Frank Vandenabeele, Paul Steels and Emmy Van Kerkhove.
2. Transforming growth factor beta 1 (TGF-ß₁) induces myofibroblast transdifferentiation in primary cultures of mouse proximal tubulus epithelial cells. Frank Vandenabeele, Sara Terryn, Marjan Moreels, Paul Steels, Emmy Van Kerkhove and Ivo Lambrichts.

11.06.2003: Posterpresentation at the World Congres of Nephrology (WCN) in Berlin (8.06.2003-12.06.2003) titled: Proximal tubular cells in primary culture, a model to study chronic cadmium exposure and interstitial fibrosis. Transdifferentiation in myofibroblasts occurs in the presence of TGF-ß₁.

21.04.2004: Oral communication and posterpresentation at the Annual Experimental Biology Meeting in Washington (16.04.2004 - 21.04.2004) titled: Mouse proximal tubular cells in primary culture transdifferentiate into æ-SMA⁺ myofibroblasts after exposure to TGF-ß₁.

08.05.2004: Oral communication at the Spring Meeting of the Belgian Society for fundamental and clinical physiology and pharmacology in Gent titled: Mouse proximal tubular cells in primary culture transdifferentiate into æ-SMA⁺ myofibroblasts after exposure to TGF-ß₁.