Dr. Ilse Smets 

Current Position

2002 - …
Post-doctoral position at the Faculty of Medicine 
Hasselt Universiteit /transnationale Universiteit Limburg, Campus Diepenbeek
Agoralaan - Gebouw D
B-3590 Diepenbeek
Belgium

University Education

1994 – 2001
Ph.D student at the Faculty of Medicine 
Hasselt University /transnationale Universiteit Limburg, Campus Diepenbeek, Belgium 
Ph. D. degree in Biomedical Sciences (December 2001)
Ph. D thesis: Cellular defence mechanisms in renal distal tubular A6 cells facing metabolic inhibition. A study of Na⁺ handling, intracellular pH, cell volume regulation and their inter-relationships.

1993 – 1995
Academic Initial Teacher Education in Applied Biological Sciences (Teaching Certificate for upper years of secondary education)
Katholieke Universiteit Leuven, Leuven, Belgium

1989 - 1994
Bio-engineer in Chemistry
Katholieke Universiteit Leuven, Leuven, Belgium


Teaching

Renal Physiology, Gastro-Intestinal Physiology, Endocrinology and Reproduction


Publications in international peer reviewed journals


Smets I.*, Zeiske W.*, Steels P., Van Driessche W. (1998)
Na⁺ dependence of single-channel current and channel density generate saturation of Na⁺ uptake in A6 cells.
Pflügers Arch - Eur J Physiol, 435, 604-609 (IF 1998 = 2.52)
*authors equally contributed to the report


Zeiske W.*, Smets I.*, Ameloot M., Steels P., Van Driessche W. (1999)
Intracellular pH shifts in cultured kidney (A6) cells: effects on apical Na⁺ transport.
Am J Physiol Cell Physiol, 277, C469-C479 (IF 1999 = 3.485)
*authors equally contributed to the report


Smets I, Ameloot M., Steels P., Van Driessche W. (2002)
Loss of cell volume regulation during metabolic inhibition in renal epithelial cells (A6): role of intracellular pH.
Am J Physiol Cell Physiol, 293, C535-C544 (IF 2002 = 3.936)


Smets I.*, Caplanusi A.*, Despa S.*, Molnar Zs., Radu M., vandeVen M., Ameloot M. and Steels P. (2004) 
Ca²⁺ uptake in mitochondria occurs via the reverse action of the Na⁺/Ca²⁺ exchanger in metabolically inhibited MDCK cells.
Am J Physiol Renal Physiol: 286, F784-F794 (IF 2002 = 5.004)
*authors equally contributed to the report

Awards

Smets I., Ameloot M., Steels P., Van Driessche W. (2000)
Effects of chemical ischemia on cell volume and on cell volume regulation in a renal distal tubular cell line (A6).
Annual meeting of The Belgian Society of Nephrology: 8 April 2000, Aalst, Belgium
Award for the best oral communication

Smets I, Ameloot M., Van Driessche W., Steels P. (2002)
High resistance of renal distal tubular A6 cells towards metabolic inhibition: role of F1F0-ATPase reversal and intracellular acidosis
The XXXIX ERA-EDTA (European Renal Association-European Dialysis and Transplant association) congress : 14-17 juli 2002, Kopenhagen, Denemarken
Congress award: 1 of the 15 best presentations in the category of ‘Basic Sciences’

Membership Scientific Associations

EKRA: European Kidney Research Association

Belgisch Genootschap voor Fundamentele en Klinische Fysiologie en Pharmacologie (Belgian society for fundamental and clinical physiology and pharmacology)